Turmeric
HerbalAlso called · 8 names▾▴
turmeric root, Indian saffron, Curcuma longa, Curcuma domestica, Curcuma aromatica, curcumin, curcuminoids, tumeric
Herbal supplement (joint symptoms)
Herbs and supplements are not FDA-approved before sale. About these sources
- Food / spice
- Capsule/tablet
- Topical
Research strength: 1 / 5
NCCIH cautions that turmeric supplements may pose a risk during pregnancy, while EMA's herbal monograph says its Curcuma longa preparations cannot be recommended because pregnancy data are lacking. MotherToBaby says moderate amounts of herbs used in food are not expected to be a concern, but its general sheet does not mention turmeric. These sources do not give first-trimester-specific human findings or separate ordinary seasoning from each supplement formulation. Ask your provider about your situation.
Last reviewed: 2026-10-16
Research strength: 2 / 5
NCCIH cautions that turmeric supplements may pose a risk during pregnancy, while EMA's herbal monograph says its Curcuma longa preparations cannot be recommended because pregnancy data are lacking. MotherToBaby says moderate amounts of herbs used in food are not expected to be a concern, but its general sheet does not mention turmeric. A 2024 case report described probable diet-related liver injury after high turmeric intake began at 23 weeks, but pregnancy-related cholestasis could not be fully excluded and liver tests became abnormal again at 35 weeks while turmeric was avoided. This single case cannot show how often this happens or whether moderate seasoning carries the same risk. Ask your provider about your situation.
Last reviewed: 2026-10-16
Research strength: 1 / 5
NCCIH cautions that turmeric supplements may pose a risk during pregnancy, while EMA's herbal monograph says its Curcuma longa preparations cannot be recommended because pregnancy data are lacking. MotherToBaby says moderate amounts of herbs used in food are not expected to be a concern, but its general sheet does not mention turmeric. These sources do not give third-trimester-specific human findings or separate ordinary seasoning from each supplement formulation. Ask your provider about your situation.
Last reviewed: 2026-10-16
Turmeric — Breastfeeding
Research strength: 2 / 5
LactMed says no data measure turmeric components in human milk, and NCCIH says little is known about amounts above those in food. LactMed cites a 50-mother trial of turmeric combined with fenugreek and ginger. It reports no infant adverse events, but says the method of checking was not reported, and the mixture cannot show turmeric's separate effect. EMA's 2018 monograph advises against Curcuma longa preparations during breastfeeding based on animal evidence of transfer and liver-enzyme changes in mouse pups, which does not establish effects in nursing people. Preclinical studies differ: a 2020 cell study found curcumin lowered milk production, while a 2026 organoid-and-mouse study found increased milk-related measures; neither tested nursing people. Ask your provider about your situation.
Last reviewed: 2026-10-16
Sources
- LactMed: TurmericUS government
- NCCIH: TurmericUS government
- EMA/HMPC: Assessment report on Curcuma longa L., rhizomaEU agencyEuropean guidance
- Singh et al., Cancer Letters 1995: animal lactation studyUS government
- Bumrungpert et al., Breastfeeding Medicine 2018: mixed-herb randomized trialUS government
- Kobayashi et al., Phytomedicine 2021: lactating mammary-cell studyUS government
- Zhou et al., Biomaterials 2026: mammary organoid and mouse studyUS government
Pregnancy
NCCIH cautions that turmeric supplement use may pose a risk during pregnancy. EMA's 2018 HMPC report says pregnancy outcomes have not been established and that Curcuma longa preparations cannot be recommended because relevant data are lacking. MotherToBaby's general herbal-products sheet says moderate amounts of herbs used in food are not expected to be a concern, but it does not name turmeric. The only turmeric-specific human pregnancy report located was a 2024 case of maternal liver injury after the patient reported consuming turmeric 3 to 4 times daily, in amounts reported as 5 to 10 grams, beginning at 23 weeks and 4 days. The authors called the diet-related injury probable, but intrahepatic cholestasis of pregnancy could not be fully excluded; liver tests became abnormal again at 35 weeks while turmeric was avoided. This single case does not establish how often injury occurs or whether ordinary seasoning has the same effect. The 2025 network meta-analysis addressed nutritional supplements in women with infertility, not routine exposure during established pregnancy. A 2026 recurrent-loss study used an RSA mouse model and human endometrial stromal cells, not clinical miscarriage outcomes. No trimester-specific human outcome studies were identified.
Breastfeeding
LactMed reports no human milk measurements for turmeric components and no infant-level data. It cites a randomized trial of 50 exclusively breastfeeding mothers, 25 per group, who used a mixed supplement containing fenugreek, ginger, and turmeric for 4 weeks. LactMed reports that no infant adverse events were reported, but that the method used to determine this was not described; infant growth was not reported. The primary abstract reports no difference in adverse effects between groups, and the combination does not identify turmeric's individual effect. The trial reported a 49% increase in pumped milk volume at week 2 and a 103% increase at week 4 in the supplement group compared with baseline, but these changes cannot be assigned to turmeric alone. A 1995 mouse study found changes in liver-enzyme markers in nursing dams and pups after high doses and said this suggested transfer through milk. A 2020 in vitro study found curcumin reduced milk production in lactating mammary cells. A 2026 study found increased lactogenic signals in human mammary organoids and increased milk yield in a postpartum mouse model. None of these studies establishes effects in nursing people.
Turmeric is the rhizome of Curcuma longa and is used as a food seasoning. Curcumin is one of several curcuminoids found in the rhizome and is also sold as a concentrated supplement. Supplement ingredients and amounts vary. Some products add piperine from black pepper or use other formulations to increase curcumin absorption, so these products are not the same as ordinary seasoning. The 2026 FSA/FSS assessment concerned a purified, hydrogenated curcuminoid ingredient, not turmeric powder or a standard curcumin extract.
What was tested
Pregnancy evidence is limited to one case report of possible maternal liver injury after high turmeric intake; it does not provide comparative fetal or newborn outcomes. The 2025 infertility network meta-analysis and 2026 recurrent-loss paper do not test routine turmeric use during human pregnancy. Breastfeeding evidence includes one small randomized trial of a three-herb product, with no turmeric-only group and no reported infant growth. No human milk concentration data were identified. The milk-production literature includes an in vitro cell study and a later human-organoid and postpartum-mouse study with differing findings. Liver-injury reports include selected case series, which do not estimate the rate among users.
Pregnancy advice for food amounts versus supplements
- Source A says
- NCCIH cautions that turmeric supplements may pose a risk during pregnancy. EMA's herbal monograph says its Curcuma longa preparations cannot be recommended because pregnancy data are lacking. (NCCIH: Turmeric, EMA/HMPC: Assessment report on Curcuma longa L., rhizoma)
- Source B says
- MotherToBaby says moderate amounts of herbs used in food are not expected to be a concern, but its general sheet does not discuss turmeric specifically. (MotherToBaby: Herbal Products fact sheet)
- Why they differ
- The sources address different forms and evidence. NCCIH names supplements, EMA addresses medicinal preparations and cites missing pregnancy data, and MotherToBaby gives general advice about moderate food use rather than turmeric-specific findings.
- What the evidence shows overall
- The evidence does not establish pregnancy outcomes for turmeric supplements or provide trimester-specific human data. EMA's recommendation reflects missing data, and the general food statement is not specific to turmeric. The pregnancy rating remains insufficient; ordinary seasoning and concentrated supplements should not be treated as interchangeable.
EMA's breastfeeding precaution and limited human evidence
- Source A says
- EMA advises against Curcuma longa preparations during breastfeeding, citing an animal study in which liver-enzyme changes in nursing pups suggested transfer of turmeric or curcumin constituents through milk. (EMA/HMPC: Assessment report on Curcuma longa L., rhizoma, Singh et al., Cancer Letters 1995: animal lactation study)
- Source B says
- LactMed reports no human milk measurements for turmeric components, and NCCIH says little is known about amounts above those found in food while breastfeeding. (LactMed: Turmeric, NCCIH: Turmeric)
- Why they differ
- EMA applies a precaution based on an animal signal. LactMed and NCCIH describe the lack of human milk data. The animal findings do not establish transfer levels or effects in nursing people.
- What the evidence shows overall
- EMA's advice should be shown, but the animal study does not establish human infant harm at ordinary use. Human data remain insufficient, so the live rating stays insufficient.
Curcumin and milk production in experimental models
- Source A says
- A 2020 in vitro study found that curcumin reduced milk production in lactating mammary epithelial cells. (Kobayashi et al., Phytomedicine 2021: lactating mammary-cell study)
- Source B says
- A 2026 study found increased lactogenic signals in human mammary organoids and increased milk yield in postpartum mice. A 2018 human trial also found increased pumped milk volume with a mixture containing turmeric, fenugreek, and ginger, but could not isolate turmeric's effect. (Zhou et al., Biomaterials 2026: mammary organoid and mouse study, Bumrungpert et al., Breastfeeding Medicine 2018: mixed-herb randomized trial)
- Why they differ
- The studies used different models and outcomes, including cells, organoids, mice, and a mixed-herb human product. None tests turmeric by itself in nursing people.
- What the evidence shows overall
- The preclinical findings point in different directions, and the human trial cannot attribute its results to turmeric. They do not establish whether oral turmeric changes milk production in nursing people.
- MotherToBaby advises discussing herbal products and the reason for using them with a healthcare provider during pregnancy. (MotherToBaby)
- NCCIH advises people taking medicines to talk with a healthcare provider before using an herbal product because herbs and medicines can interact. (NCCIH)
General research, not specific to pregnancy.
LiverTox and EMA describe liver-injury reports linked especially to concentrated curcumin products designed to increase absorption or used at high doses. The DILIN and pathology series describe selected cases, not how often injury occurs among users. EMA's 2025 review reported no liver injury at the EU monograph doses and did not recommend changing the monograph.
- The 2023 DILIN series described 10 turmeric-associated liver-injury cases; 5 patients were hospitalized and 1 died. These selected cases do not estimate the rate among users. (Halegoua-DeMarzio et al., American Journal of Medicine 2023: DILIN case series)
- A 2025 pathology series identified 11 patients with turmeric supplement-associated hepatitis; causality was rated probable in 8 cases and possible in 3. This selected series is not an incidence estimate. (Papke et al., Histopathology 2025: turmeric supplement-associated hepatitis case series)
- EMA's July 2022 PRAC minutes asked the edotreotide product holder to include any new information on a possible curcumin or turmeric interaction in its next safety report. This was a request to monitor new information, not a finding that an interaction had been confirmed. (EMA PRAC minutes, 4 to 7 July 2022: edotreotide PSUR assessment)
- The 2026 FSA/FSS assessment covered purified, hydrogenated tetrahydrocurcuminoids, a different supplement ingredient from turmeric powder or standard curcumin extract. The assessment excluded pregnant and lactating people and said liver injury could not be fully ruled out for some susceptible users, even below the proposed 140 mg daily maximum. (Food Standards Agency and Food Standards Scotland: tetrahydrocurcuminoids novel food assessment)
- MotherToBaby: Herbal Products fact sheetTeratology serviceSecondaryIndependent check
- NCCIH: TurmericUS governmentSecondaryIndependent check
- LactMed: TurmericUS governmentSecondaryPage dated 2025-07-15
- EMA/HMPC: Assessment report on Curcuma longa L., rhizomaEU agencySecondaryPage dated 2018-09-25Independent checkEuropean guidance
- Haloub et al., Case Reports in Hepatology 2024: high-dose turmeric case reportUS governmentPrimaryIndependent check
- Singh et al., Cancer Letters 1995: animal lactation studyUS governmentPrimaryIndependent check
- Bumrungpert et al., Breastfeeding Medicine 2018: mixed-herb randomized trialUS governmentPrimaryIndependent check
- Kobayashi et al., Phytomedicine 2021: lactating mammary-cell studyUS governmentPrimaryIndependent check
- Zhou et al., Biomaterials 2026: mammary organoid and mouse studyUS governmentPrimary
- Du et al., 2025: network meta-analysis of supplements in female infertilityUS governmentPrimary
- Ma et al., Food Science & Nutrition 2026: recurrent-loss preclinical studyUS governmentPrimary
- LiverTox: TurmericUS governmentSecondaryPage dated 2025-06-16Independent check
- Halegoua-DeMarzio et al., American Journal of Medicine 2023: DILIN case seriesUS governmentPrimaryIndependent check
- Papke et al., Histopathology 2025: turmeric supplement-associated hepatitis case seriesUS governmentPrimaryIndependent check
- EMA/HMPC: 2025 addendum to the Curcuma longa assessment reportEU agencySecondaryPage dated 2025-11-19Independent checkEuropean guidance
- EMA PRAC minutes, 4 to 7 July 2022: edotreotide PSUR assessmentEU agencySecondaryEuropean guidance
- Food Standards Agency and Food Standards Scotland: tetrahydrocurcuminoids novel food assessmentUK governmentSecondaryPage dated 2026-04-29
Last reviewed 2026-10-16
Independent check 2026-10-16
Not yet clinician-reviewed
Ask your provider about your situation.
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